Petechial, purpuric, and ecchymotic presentation of cutaneous Cryptococcus in mantle cell lymphoma
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Petechial, purpuric, and ecchymotic presentation of cutaneous Cryptococcus in mantle cell lymphoma
MCL: mantle cell lymphoma INTRODUCTION Cryptococcus neoformans is an encapsulated, ubiquitous fungus that can infect the skin. Cutaneous Cryptococcus usually occurs after dissemination of a respiratory infection but can result from direct contact to the skin. Although classically seen in HIV-infected patients, cryptococcal infections also occur in HIV-negative individuals with or without other ...
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Mantle cell lymphoma is a type of non-Hodgkin lymphoma that affects extranodal areas, especially, bone narrow, digestive tract and Waldeyer ring. Here we report a case of mantle cell lymphoma IV Ann Arbor stage with cutaneous lesions on nasal dorsum and glans penis as the first manifestations. Skin involvement is a very rare manifestation and less than 20 cases have been reported in the literat...
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Eighteen cases of mantle cell lymphomas (MCL) with an atypical t(11;14) were studied using fluorescence in situ hybridization experiments (FISH). The atypical presentation was confirmed and unsuspected duplicated cases were identified in six patients. These data underline that FISH analysis must be be systematically performed in cases with an aberrant presentation to prevent a misdiagnosis.
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Background While 2% of all extranodal Non-Hodgkin Lymphomas present in the thyroid, there exists insufficient data to describe the incidence of mantle cell lymphoma in the thyroid. A case series of 1400 patients revealed that <1% of thyroid lymphomas may be MCL; hence better understanding of the disease course is essential. Patient Findings A 65-year-old female was referred for a multinodular...
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Mantle cell lymphoma is molecularly characterized by the chromosomal translocation t(11;14) (q13;q32) that results in a constitutional overexpression of the cell cycle regulator protein cyclin D1. Generally, the disease is characterized by rapid relapses and poor long-term outcome. However, a subset of patients with indolent disease has been identified. Randomized trials have demonstrated the s...
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ژورنال
عنوان ژورنال: JAAD Case Reports
سال: 2017
ISSN: 2352-5126
DOI: 10.1016/j.jdcr.2016.12.001